Melanotan has been around in the market for years. But not all people are aware of the differences between MT-1 and MT-2, and which is better Melanotan 1 or Melanotan 2?
By nature, we use the natural processes for actions that benefit the body. What about tanning under the sun? Most people fear to tan under the UV rays. Luxembourg Research has suggested you can get a darker skin pigmentation without UV exposure with the use of Melanotan products as a tanning agent.
Melanotan 1 and Melanotan 2 are synthetic analogues of the naturally occurring hormone alpha-melanocyte-stimulating hormone (α-MSH). This hormone plays a crucial role in stimulating the production of melanin, the pigment responsible for skin colour. Developed initially for skin cancer prevention, these peptides have piqued the interest of those seeking a tan without sun exposure.
Melanotan 1, also known as Afamelanotide, is primarily used for medical purposes. It has been studied for its potential in treating skin conditions such as erythropoietic protoporphyria, a rare genetic disorder that causes sensitivity to light. On the other hand, Melanotan 2 is more commonly associated with cosmetic use, offering a broader range of effects beyond tanning.
Melanotan 1 and Melanotan 2 are synthetic peptides that stimulate melanin production. Melanotan 1 requires more dosage but has fewer side effects, while Melanotan 2 is more potent, requires less dosage, and has a shorter half-life. Choosing between them depends on personal preference and desired results.
This peptide is a synthetic hormone that mimics the effects of the body’s natural tanning process without UV light. A melanotan injection stimulates the melanin production, the pigment that gives your skin its colour. This peptide is available in two forms: Melanotan 1 and Melanotan 2 for research use.
Naturally, the human body produces melanocyte-stimulating hormone, activating its natural pigmentation. With two weeks of intake, Luxembourg research has suggested you can see and feel that perfect tan.
For men, MT-2 also boosts energy, stamina, sexual desire, sexual stimulation, and arousal; however, Peptide PT-141 is much more suited to increasing sex drive and its efficacy in enhancing sexual performance. Female users, on the other hand, overcome their sexual dysfunction.
As an advanced form of MT-1, Melanotan 2 Luxembourg serves as an excellent tool to ward off skin issues. It boosts the amount of melanin in the body that darkens the skin. Compared to MT-1, MT-2 is more potent, which targets melanocortin receptors. It has a cycle of amino acids that separates it from the other peptides, which in turn, Luxembourg research has suggested can promote better absorption.
Both Melanotan 1 and Melanotan 2 work by stimulating melanocortin receptors in the body. These receptors are located in various tissues, including the skin, and play a pivotal role in regulating melanin production. When the peptides bind to these receptors, they trigger a cascade of reactions that result in increased melanin synthesis.
For Melanotan 1, the primary mechanism is its affinity for the MC1R receptor, which is directly involved in skin pigmentation. This targeted approach is why it is favoured for medical treatments where precise effects are needed.
Melanotan 2, however, interacts with multiple melanocortin receptors, including MC3R and MC4R. This broader interaction explains its additional effects on sexual arousal and appetite. By influencing these receptors, Melanotan 2 can produce outcomes that extend beyond skin pigmentation. Tanning peptides are specifically discussed in our blog, looking at the cosmetic industry and legalities of tanning peptides.
Both MT-1 and MT-2 can cause serious side effects, such as nausea, vomiting, and increased blood pressure. However, MT-2 is more likely to cause side effects because of its higher potency.
Melanotan 1 and Melanotan 2 are both effective tanning peptides, but they have some key differences. MT-1 is generally considered to be safer and more effective for maintaining a long-lasting tan, while MT-2 is more potent and can produce faster results.
The legal status of the human use of Melanotan 1 or Melanotan 2 peptide can vary by country and region, with some places classifying it as a regulated substance due to safety concerns and misuse risks. In some jurisdictions, Melanotan may be considered a controlled substance due to its unapproved use for cosmetic purposes like tanning by the department of health and FDA, despite social media influencers promoting it as a ‘barbie drug’. It’s essential for individuals to research and understand the specific laws and regulations regarding Melanotan peptide in their location before considering its purchase or usage.
PharmaGrade store Luxembourg supplies peptides for medical research purposes only.
[1] Zhang JJ, Meng X, Li Y, Zhou Y, Xu DP, Li S, Li HB. Effects of Melatonin on Liver Injuries and Diseases. Int J Mol Sci. 2017 Mar 23;18(4):673.
[2] Dorr RT, Lines R, Levine N, Brooks C, Xiang L, Hruby VJ, Hadley ME. Evaluation of melanotan-II, a superpotent cyclic melanotropic peptide in a pilot phase-I clinical study. Life Sci. 1996;58(20):1777-84.
[3] Dorr RT, Ertl G, Levine N, Brooks C, Bangert JL, Powell MB, Humphrey S, Alberts DS. Effects of a superpotent melanotropic peptide in combination with solar UV radiation on tanning of the skin in human volunteers. Arch Dermatol. 2004 Jul;140(7):827-35.
[4] Wessells H, Levine N, Hadley ME, Dorr R, Hruby V. Melanocortin receptor agonists, penile erection, and sexual motivation: human studies with Melanotan II. Int J Impot Res. 2000 Oct;12 Suppl 4:S74-9.
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